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hsa-mir-302a: Hsa-mir-302a is one of the miRNAs included in a prognostic model for neuroblastoma, along with hsa-let-7c, hsa-miR-93, hsa-miR-195, hsa-miR-137, hsa-miR-197, hsa-miR-15a, hsa-miR-149, hsa-miR-331, hsa-miR-135a, and hsa-miR-204 [PMC9278893]. The miRNA mimic sequence for hsa-mir-302a is 5′-ACU UAA ACG UGG AUG UAC UUG CU -3′ [PMC9497224]. Applied Biosystem's TaqMan microRNA assays were used to detect and quantify mature microRNAs including hsa-mir 302a [PMC3441572]. Hsa mir 302a was found to be significantly downregulated in certain conditions [PMC4055138]. HSA mir 302a has been shown to regulate vasculogenic targets and act as a tumor suppressor and repressor of cell division. One of its direct targets is VEGFA [PMC6884596]. The luciferase activity in cells transfected with the reporter vector containing the DAZAP2 3'-UTR was significantly decreased by >60% following cotransfection with mimics of HSA mir 302a -d but not with a mimic of HSA miRNA367 [PMC7251312].
mRNA interactions
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Gene Ontology annotations
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