Sorry, there was a problem loading sequence from server. Please try again and contact us if the problem persists.

Mus musculus (house mouse) mmu-miR-322-3p URS00000565C2_10090

Caution, this is an AI generated summary based on literature. This may have errors, see here for more. Please share your feedback with us.

mmu-mir-322: Mmu-mir-322 is a microRNA that is upregulated in the thymus and is associated with the modulation of cellular metabolism [PMC9198802]. It has been found to be orthologous to human miR-424 and has been shown to protect hearts in mice from the effects of a high-fat diet [PMC5979329]. In various studies, expression levels of mmu-mir-322 have been evaluated, and it has been found that levels of miR-17, miR-21, and miR-223 were reduced while levels of mmu-mir-322 were increased [PMC4731388]. High expression of mmu-mir-322 has also been associated with cell differentiation, folliculogenesis, and ovarian development [PMC4499447]. On the other hand, down-regulation of mmu-mir-322 has been observed in the context of endoplasmic reticulum stress and the unfolded protein response [PMC6291480]. Computational target prediction analysis suggests that mmu-mir-322 does not directly bind to genes associated with Nox2 or its regulation [PMC6356993]. Mmu-mir-322 has also been found to be more prominent in regulatory networks and may play crucial roles in various biological processes [PMC3692539][PMC3767082][PMC5544724][PMC4069098][PMC3540168][PMC7386314]. It is highly expressed in placental tissue and its abundance can be quantified using qRT-PCR [PMC6366741]. In response to IFN-gamma treatment, mmu-miR-29a/b was downregulated while mmu-mir-322 was upregulated [PMC5543588].

Genome locations

Gene Ontology annotations

Sequence

Sequence features are shown above as colored rectangles. Zoom in and click to view details, or Reset

Search for similar sequences
AAACAUGAAGCGCUGCAACAC

Taxonomic tree

View annotations in different species by clicking on species names.

Scroll around to explore the entire tree. Click tree nodes to collapse or expand them. Hover over taxon names to display additional information.

This sequence is found in 1 other species

Publications