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Homo sapiens (human) long intergenic non-protein coding RNA 1354 (LINC01354) URS0000048444_9606

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LINC01354: LINC01354 is a long non-coding RNA (lncRNA) that has been found to play critical roles in tumor progression [PMC7526132]. Silencing LINC01354 has been shown to decrease the expression of c-Myc, β-catenin, and MMP7 in vivo [PMC6463672]. This suggests that LINC01354 may have a regulatory role in the expression of these genes, which are known to be involved in tumor progression and metastasis. LncRNAs are a class of RNA molecules that do not code for proteins but have been found to have important regulatory functions in various biological processes, including cancer development [PMC7526132]. LINC01354 is one such lncRNA that has been implicated in tumor progression. In a study conducted in vivo, it was demonstrated that silencing LINC01354 led to a decrease in the expression of c-Myc, β-catenin, and MMP7 [PMC6463672]. These genes are known to be involved in cancer development and metastasis. The findings suggest that LINC01354 may play a role in regulating the expression of these genes. Understanding the functions and mechanisms of lncRNAs like LINC01354 is important for gaining insights into cancer biology and identifying potential therapeutic targets. Further research is needed to elucidate the precise mechanisms by which LINC01354 regulates gene expression and its potential as a therapeutic target for cancer treatment.

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Gene Ontology annotations

Sequence

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GCAGGGCCGACUGCAUUCCCACGGCGACGGCCUCCUGGCCCGCAUCAUGACUGUUGUUUUCCUCGCGGUGGCCAUAGCUUUUGGAUUUUACAUUCAGAUUGGUUCAAGGGGCUUUUUCCUUUCUCUGUUUGAAGGAAGCCACCCUCUCGAUCCCCAGUCAGCGUGGCGUCCUCUCAGCAACCCGCUCCUGGUCUUGCUUUGACUCCUGUGCUCCCGGGCUGCCGAGAACACGUCUGGAGCUUUUAAAUCAGGCUUUUAGGUUCAUCUCUGUGAAUAAUCAUCACAAAUAUUUACUGAGCAUCCUUCAUCUCCUGGAAGCCUCGUGGAUUAUCUUGCUGAAUCCUCACCACAGCAGCCCGCUGAGGGAGGUGCUAUCAUCGUCCCUGUUUUUCAAGGGAGAGAAUCAAGGGACAAGGUCUUGCUAUGUUGCCCAAGCUGAUCUUGAACUCCUGGCCUCAAGCAAUCCCAAUAGUUCGGUCUCCCAAAUUGCUGAGAUUGUGGGUACAAGCCACUGCACCUGGACUUCUUCUGACAUUAUAAAGCAAAGAGCAUUUUCAAAAGCUGAUGCUACUUGUGCAUAUUCCAUAUUUGCUGAGCGCUUACUGUGUCCCCAUUAAGUGCCAGGCACAGUUUUCAGCACUGCUUUAAAGUGUCUACAAGCUUAGAAAGGGCAUAGGCAUCUCUUGAAAUCCAGUGUUCUAGGGAAAGUUUUUCCUGUGGUUUUGCACAGAACCCACCGCUUCCUGUCCAAGGUGACAGCUUUAGCUGGGAGAGAAAUUAAAAAUGCCUCCUUGGAAUAGCUAUCUGAUGUGUCUAAAUAUGAUUGCUGAUGUUAGCAAUAGGACCUGCCUAUUAGCAAUGGUUUGGGCAACUGUAUGUGUGAGGCAGGGAGAGAAAGAGGAAGAAAAUACAGCUCUCACUAUUGUUUCCAAAUGGCAAGACUGGUUUUCCUGCUACCUACUAACCAGUGUAGUUAUUAGUGUUACAUAUCACCUCUGCAUCUUAUUUAUGUAAUAUUCCAAGAAGCUAAAAAAAAAAACCUCUUUUUUUUUUUUUUUUUACAAAUCUUAGAUUUUAUGAACACUUGCUAAUAGCCCCCCCCUCCUAGAUCGUCAUUGCUGUGUAACAAAUUGUCAUACAUUUAGCAGUUUAAAAUACCACACAUUUACUCACAGCUUCCAUGGGCCACGAGUGUGGGGACGAGUGACUGGGUCGUCUGCUCAGGGUCUCUUACAAGACUCCAUCAGCGUUUCAGCUGGGGCUGGGGUCUCAUCUGAGGCUCAGGGUCCUCACUCCAGGUCACAGGGCAGAAUUCAUUUCUUUCAAGCUACGGAUCUCAUGGCAGCUUGCUUUUUCAAGGCCAGCAAGGGAGAGAGUGAAUCUGCUGCUUUUAGUGUCUGACCUCUCGAUCUUCUUUUAAAUGGCUCAUCUGAUUAGGGCAGACCCACCCAGGAUAAUCUCUCUUUUGACUAACUUACAGUCAACUCAUUAGAGAUCCUAAUUACAUCUGCAAAAAUCCCCUCACCUUUGCCUGAUAAUGUGACAUCAUCACGGGGGCAAUAUCCCAUCACUUUUGCCAUAUACUAUUGGCUAGAAGCAAAUUAAGGUCCUGCUACCACUCAAGGGGAGGGGAUUACACAAGGGCAUGGGACAUCAGGGGUCAUCUUAGAAUUCUGGCAACCAGAAUAAGCUACUUGUGGAUAGACAUGUUGUCAUACAUAUUUUUUGUUCAGUCAUUAUGCUUAGCAGAGAAAUAGGCACACAGCAGAAAAAUAACUGAUUGGUACGGAGAAUUUAGUGAUUGGAAACGAAUUAAUAUUGUUAAGACACAAAGUUUCUUGCAGAGCACACUCUGAAAAAGGUCACUUUUUACCCCUCAAUAUGUCUUAAUGGGUUGAGGUAGAGAGAAGCGUGGGUAGGUAUCAAUCACGAGAGCACACAGGCUAAAAGAAAGAAAAAAUGAGCUGGGACAUCUAAGUUCAACUUCCACUUCCUCCUAUACAAGCUGGGUGACCUUUUCCUAUCUAGAAAGUGGGAGAAGUAGUUCCUGUCCUCCCUUACAGGGCUGCUGAGCAGGCAGAAUGAGAUGAUGGGCUGAGAGGGCUUGGAGAGGACAAACUGUGGGUACAAAAGUCUUAUUGUCCUGGCCCGGAUUGCUAAGGAGAUGGUGGUUAAUAAUAUGCUGCUAUCUCAUGAGGUAAAUGCGUGAUCACAUAGCCAAGAGAUGCCUUUUUGUUCUAAUGAUCACUGUAAGACCUUCUUGAGAGACAGUCCAAGUCUCUCCAGCACAAUGGAAAAUUGCAUUUUCUAUGCACACAUUCGAGGGGAAAGAGACCCCUCCAACGUUCUUCUCAGUUUUACCCCAAAGUUGAGUUCUGGGUCAAAAAUCUCUCAAGCGUCCUCCACAGCUGACUUCCACAGUCCCCUGUGUGUCUCUGCAAGGAACACAAAGGAAGUGAGAUAGUGGGAAGUCUGGGGCCAUCUUCGGUCACGUGAGAAUUCCCUCUCAGUUAGCCGGGGCGUGCAGCCGCACAGAAGGAAGGCAGCCACGCAGCUCCAGUCCAGGCUGGGAGAGAGCUUUGUAGAUCCAUCUCCCACUGAGCAGGCUUCCCUCCUGCAAGGAGAGACUCUACCGAUAAUGUGUUAAGAUCAGAUUAAUGCAGGAAAUACACAUGAAAUAAAUAAUAACAGUGUAAUAACAGUGGCUGUCAUUGCAAUGGUUAUUUCUGUUAAAAAUGUGAGAUCUACACUACGGAUUUCUUAGGAUAAUUUUGCCCUUACUUAAAAGAAACUGACAGAUGUACUUUAUAAAAAUGAAAAUAAUUUAACAAAUAAAGAAUUGGAGAAUAUUGACUCACCA

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