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Homo sapiens (human) hsa-miR-141-3p URS000003E1A9_9606

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hsa-mir-141: Hsa-mir-141 is a microRNA that is found to be overexpressed in cisplatin resistant ovarian, gastric, and esophageal squamous cancer cells [PMC4682251]. In a study, gene expression levels of hsa-mir-141 were quantified using specific primers [PMC4981873]. The study used primers for hsa-mir-141 (#204504) and hsa-miR-200c (#2044852) from Exiqon [PMC4981873]. The overexpression of hsa-mir-141 in cisplatin resistant cancer cells suggests its potential role in drug resistance mechanisms [PMC4682251]. This microRNA may be involved in regulating gene expression and signaling pathways that contribute to resistance against cisplatin treatment [PMC4682251]. The quantification of gene expression levels using specific primers allows for the accurate measurement of hsa-mir-141 expression levels [PMC4981873]. This information can be valuable for understanding the mechanisms underlying drug resistance and developing targeted therapies to overcome it [PMC4981873]. Further research is needed to elucidate the specific targets and pathways regulated by hsa-mir-141 in cisplatin resistant cancer cells [PMC4682251]. Understanding the role of this microRNA can provide insights into potential therapeutic strategies for improving treatment outcomes in ovarian, gastric, and esophageal squamous cancers [PMC4682251].

mRNA interactions 7 total

Genome locations

Gene Ontology annotations

Localisation

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UAACACUGUCUGGUAAAGAUGG

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This sequence is found in 8 other species

  1. Bos taurus (cattle) bta-miR-141
  2. Capra hircus chi-miR-141
  3. Equus caballus (horse) eca-miR-141
  4. Mus musculus mmu-miR-141-3p
  5. Ovis aries miscellaneous RNA
  6. Pan troglodytes ptr-miR-141
  7. Pteropus alecto (black flying fox) pal-miR-141-3p
  8. Rattus norvegicus rno-miR-141-3p
Publications