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Hsa-Mir-1269: Hsa-mir-1269 is a miRNA that has been studied in various contexts. It has been constructed using chemosynthetic oligonucleotides and inserted into a plasmid [PMC6873743]. In a study on prognostic factors, hsa-mir-1269 was identified as one of the miRNAs associated with overall survival in patients with EC [PMC9200351]. It was also found to be potentially associated with alcohol-related EC [PMC9200351]. In another study, hsa-mir-1269 was assessed along with other miRNAs using the miRNA PCR Array, and its serum levels were measured [PMC5467072]. Furthermore, hsa-mir-1269 was found to be significantly involved in hepatocellular carcinoma (HCC) [PMC7467934]. Additionally, hsa-mir-1269 was identified as one of the differentially expressed miRNAs in a study using TCGA data [PMC5950030]. Finally, hsa-mir-1269 was found to have anti-correlated mRNA levels for several genes in a specific grouping [PMC4175465].
hsa-mir-1269a: Hsa-mir-1269a is a microRNA that has been implicated in various biological processes and diseases [PMC5952075]. In the context of ectopic pregnancy, a study using COX regression analysis found that abnormal expression levels of hsa-mir-1247 and hsa-mir-1269a, as well as salpingitis, may be risk factors [PMC5952075]. While the functional roles of the other three microRNAs in clear cell renal cell carcinoma (ccRCC) are still less reported to date, some other studies have revealed that hsa-mir-1269a could function as an onco-miRNA in non-small cell lung cancer (NSCLC) by down-regulating its target gene SOX6 [PMC6895828].
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